Product information:

Amlodipine besylate belongs to a group of medicines called calcium channel blockers. These dilate the blood vessels

in the body  and are used to treat high blood pressure and angina.Amlodipine besylate is a product of Pharmaceutical Intermediates.

Product name: Amlodipine besylate

Other name: Amlodipine benzenesulfonate

Appearance: White powder

CAS NO.: 111470-99-6

M.F.: C26H31ClN2O8S

M.W.: 567.051

Grade: Pharmaceutical grade

product Photo:

Amlodipine Besylate CAS No 111470-99-6

Items	Spectfication	Analytical results
Characteristic
Appearance	White or almost white powder	Almost white powder
Identification
A.Infrared absorption	The IR spectrum of the sample corresponds to the IR spectrum of the RS	The IR spectrum of the sample corresponds to the IR spectrum of the RS
B.Identity test	The retention time of the assay preparation corresponds to the standard preparation	The retention time of the assay preparation corresponds to the standard preparation
Tests
Optical rotation	-0.10°~+0.10°	-0.003°
Water determination	Not more than 0.5%	0.1%
Residue on ignition	Not more than 0.2%	0.05%
Related substances(HPLC)	Related compound A NMT 0.3%	Less than 0.03%
	Other than benzenesulfonic and related compound A,the total of other impurities NMT 0.3%	Less than 0.03%
Related substances(TLC)	Any spot obtained from the test solution is not greater in size than the spot obtained from standard solution(0.3%)	ND
	At most two spots are more intense than the spot obtained from standard solution(0.1%)	ND
Residual solvents	Not more than 5000ppm of ethanol	ND
Assay	Calculate on anhydrous,it contains not less than 97.0% and not more than 102.0% of C26H31ClN2O8S	100.2%
ACCORDING TO	USP 43

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