Specifications Chlorogenic acid

1. 100% natural from honeysuckle flower extract

2. Chlorogenic Acid: 10% to 98%

3. free of solvent residue

  Product Description   Brief Introduction What's Honeysucke? Honeysuckle is also knowed as Jin Yin Hua in china, is a familiar climbing flowering plant whose many varieties grow worldwide. Honeysuckle has been used medicinally in China for generations and has recently been adopted by Western herbalists. Honeysuckle is a natural source of salicylic acid, the compound from which aspirin is made, and can thus be used in cases of headache, joint pain, and fevers.   Product Name: Honeysuckles Extract
Plant sources: the dry buds or fresh opened flowers of Lonicera japonica Thunb.
Active Ingredients: Chlorogenic acid
Appearance: Powder in bright yellow to yellow-brown , or white powder / crystalline (with Chlorogenic acid content over 98%)   Specifications:
- Chlorogenic Acid: 10% ,25%, 50% , 98%
- Any other specifications can be customized   Test Method: HPLC (External standard method)
Quality Standard: Enterprise standard
Packing: 1kg/bag, 5kg/bag, or 25kg/drum or Customized.   Our Advantage:
- For products with Chlorogenic Acid content under 15%, we do not use organic solvent in the production, so they are free of solvent residue. - We have special testing technology to guarantee the acid is from Honeysuckles, instead of from other plant sources.
- No resin monomer residue.
- Using unique technology for removal of bacterium and heavy metals.
- Good water-solubility. Function&Application   1 About pharmacodynamics study
It is investigated that chlorogenicacid has a poor absorption when taken by mouth with a little part of which absorbed in small intestine while most of it will be absorbed in the terms of benzoic acid acid exists in the form of metabolites in the blood plasma. Protein binding: It is proved by test in vitro that chlogogenic acid can bind with HAS in different concentration. There is only one combine site in low concentration. It appears to be several sites in high concentration in the region of HAS and IIA. Excretion: chlogogenic acid and its metabolites in blood plasma mainly discharged through kidney but discharged along with urine when it taken by mouth.and benzene propanoic acid and cinnamic acid. Therefore chlorogenic

1) The protection to cardiovascular
A large number of experiments have show that Chlorogenic acid, as a kind of free radical scavenger and antioxidant, has a good protection to cardiovascular. Chang Cuiqing proved that chlorogenic acid has a preparatory prevention to the damage of endothelial cells induced by ox-LDL. Chlopcikova discovered that chlorogenic can protect Myocardium cell from being damaged by oxidant of Doxombiein,DOx and has a prominent inhibition of peroxidization of mitochondria envelope lipid induced by iron reserves dependence DOX. It goes to show chlorogenic acid can protect vascular endothelium cell by removing radical intermediate and antioxidant lipids and has a further prevention to arteriosclerosishypertension and thrombosis.

2) Anti-mutagens and anti-cancer
The experiment of animals shows that chlorogenic acid can prevent and inhibit colon cancer and stomach cancer. Jiang discovered chlorogenic acid brought bigger DNA fragments produced by tumor cells and its agglutination. Aryl hydrocarbon hydroxylase is an important Metabolizing Enzyme of polynuclear aromatic and its activeness would improve the mutagens of anti- polynuclear aromatic of tissue cells. Research in vitro discovered that chlorogenic acid can improve the activeness of Aryl hydrocarbon hydroxylase. It also can inhibit the formation of 8-OHdG and the grow of Escherichia foetidaStaphylococcus aureusblack hay bacillus and legionella.

3) Reduce blood fat
Veins have given chlorogenic the power of reducing cholesterol and triglycerides in the blood of rats. When adding chlorogenic acid to the food of rats, it discovered that the cholesterol in rats lungs and livers has also reduced.

4) Anti-leukemia
Chiang found that chlorogenic acid had light activeness of anti-leukemia by the experiment in vitro. J. Bandyopadhyay has proved that chlorogenic acid can inhibit Ber-Abl and c-Abl and induce the dead of the original lymphocytosis in the body of leukemia patients.

5) Adjust the immune function
The research in vitro has showed chlorogenic acid can obviously strengthen T cells caused by influenza as well as induce humans lymphocytes and albumen cells to produce 7-IFN and α-IFN. It can improve the lgG1 and Ll4 level of rats. In a recent research, it is discovered that chlorogenic acid has the ability to activate nerve cardiac troponin to strengthen the function of macrophages.

6) Lower glucose
It is proved by the research of Andrade-Cetto and Wiedenfeld H that
Chlorogenic acid has potential function in lowering glucose in animals body. The function may have relationships with the inhibiting of glucose-6- and the absorption of glucose.   Effects:
- Immune regulation and anti-tumor
- Anti-oxidation, free radical scavenging
- Anti-bacterial , anti- inflammatory
- Lowering blood glucose level
- Lipid-decreasing

Applications:
- Functional food additive & health supplement
- Pharmaceuticals
- Cosmetics & personal care products
- Feed supplement   Products Show  

Company Information   Hunan Zhengdi Biological Resources Development Co.,Ltd. concentrates on the high-efficient comprehensive development of plant resources and their deep-processing products. We are a manufacturer, a high-tech enterprise with enormous experience in research and development, as well as abundant plant resources.   Focusing on R&D and keep improving We have made a breakthrough on processing technology in order to meet the limits of microorganism and heavy metal content. We have experiences on R&D of medicine and health food for over 10 years, and our advantage are research on preparation technology, quality standard and study on general pharmacology & toxicology. Outstanding advantages on controlling the resources We have own planting base of herbal medicines and cooperate with professional herbal medicine cultivation institutions. The cultivation is strictly according to the requirements of Chinese GAP standard. To ensure the raw material quality, harvest season, field processing, storage and transportation are also strictly controlled. Outstanding achievements on quality management Our company has built the GMP plant completely complying with Good Manufacture Practice in Hunan Zhanda Taikang Pharmaceutical Co., Ltd. and has the relevant Chinese drug GMP certificate. Production is strictly conducted according to Good Manufacture Practice. All the procedures are regulated by relevant GMP documents, from the purchase of raw material to sales of the finished product, to ensure the traceability of the whole production process in order to guarantee the product quality. Leading talent pool in the industry Our Management team has abundant pharmaceutical professional background, and main supervisory technical staffs have application and registration experiences of medical products and health-related products for ten years and can accurately grasp the requirements of policies, regulations and technical principles of medical products and health-related products.   Our Services                      Click Our below hot produts for more details, Your inquiries are welcome!